Does Codeine Show Up on Urine test?

Evidence-based answer reviewed against SAMHSA cutoffs and FDA assay documentation · Updated August 2026

Quick answer: On a urine test, Codeine typically registers for 1–3 days (codeine) after last use. ('Urine remains the employment default because it balances cost, window-length and legal defensibility. Metabolite CONCENTRATIONS (not presence/absence) decide results against cutoff tables, which is why hydration status moves numbers and why validity checks (creatinine, specific gravity) police dilution attempts.',)

How urine testing catches Codeine

('Urine remains the employment default because it balances cost, window-length and legal defensibility. Metabolite CONCENTRATIONS (not presence/absence) decide results against cutoff tables, which is why hydration status moves numbers and why validity checks (creatinine, specific gravity) police dilution attempts.',)

Covered by the standard opiate strip: 2,000 ng/mL morphine/codeine.

Compare all specimens

Ranges reflect occasional-to-heavy use patterns from FDA device inserts and SAMHSA-certified lab conventions.
Test typeTypical Codeine detection window
Urineany: 1–3 days (codeine)
Saliva (Mouth Swab)any: 1–2 days
Hair Folliclesup to 90 days
Bloodany: ~12–24 hours

Context worth knowing

Lean's codeine lands squarely on the classic opiate panel — this is one street drug standard testing catches without any expansion.

Promethazine itself isn't screened, but it can flag old-generation amphetamine screens as a false positive; confirmation sorts it out.

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Medical disclaimer: DrugPanels provides educational information about laboratory drug testing and does not offer medical advice, diagnosis, or treatment. Detection windows are population ranges — individual results vary with metabolism, dose, frequency and health status. Never stop prescribed medication to pass a test without talking to your prescriber. Affiliate disclosure: some links on this page are affiliate links; if you order through them we may earn a commission at no additional cost to you.

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Does Codeine Show up in a Urine Drug Test?

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Will Codeine Show up in a Urine Drug Test?

Yes — Codeine sits on standard 5/10/12-panel screens. Prescription? Declare it for MRO verification.

Do prescriptions count against me?

No — verified prescriptions report as negative through the Medical Review Officer. Declare medications at collection and answer the follow-up call.

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Sources & further reading

  • SAMHSA — Mandatory Guidelines for Federal Workplace Drug Testing Programs (cutoffs, MRO process)
  • DOT — 49 CFR Part 40 procedures for transportation workplace testing
  • Brahm NC et al., Mayo Clinic Proceedings 2008;83(1):66–76 — false-positive cross-reactivity reference
  • FDA — drug-of-abuse test device labeling (detection window conventions)