Is Marijuana Legal in South Carolina?

Evidence-based answer reviewed against SAMHSA cutoffs and FDA assay documentation · Updated September 2026

Quick answer: Yes, with a medical card. South Carolina passed a limited medical cannabis law in 2024, but the program was not yet operational as of 2026. Adult-use marijuana remains illegal. Employers may still enforce drug-free workplace policies and test employees.

South Carolina at a glance

ItemStatus
Medical program established2024
Recreational home cultivationNot allowed

Employer protections & drug testing

South Carolina does not broadly protect off-duty cannabis use in employment; employers may still enforce drug-free workplace policies and test under state law.

Even in legal states, employers may still drug test and set workplace policies. Off-duty protections vary widely and federal-adjacent roles keep zero-tolerance.

What it means for a drug test

South Carolina allows workplace drug testing and employers may act on positive results. A medical card does not shield an employee from testing, and state law does not require employers to accommodate off-duty use.

Sources

Status and limits verified against official state statutes and advocacy trackers. Laws change — always confirm with the primary source before relying on this page.

  • South Carolina Code (Compassionate Care Act)
  • MPP state map
  • NORML state laws

More states

See the full marijuana legality by state chart and the does weed show up on a drug test? guide.

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Sources & further reading

  • SAMHSA — Mandatory Guidelines for Federal Workplace Drug Testing Programs (cutoffs, MRO process)
  • DOT — 49 CFR Part 40 procedures for transportation workplace testing
  • Brahm NC et al., Mayo Clinic Proceedings 2008;83(1):66–76 — false-positive cross-reactivity reference
  • FDA — drug-of-abuse test device labeling (detection window conventions)