Quick answer
NBOMe (25I-NBOMe) is typically detectable in urine for roughly 6–24 hours (specialised assay) after any use. It is not part of standard employment panels.
Not screened on standard employment panels.
Typical cutoff: Not on standard panels; requires a dedicated LC-MS/MS assay. Urine detection is typically short, often under 24 hours.
Detection window by test type
| urine | |
|---|---|
| Any use | roughly 6–24 hours (specialised assay) |
| saliva | |
| Any use | limited data |
| hair | |
| Any use | detectable on specialised testing |
| blood | |
| Any use | hours |
Ranges reflect typical published detection windows and vary with dose, frequency, body composition, hydration and the assay used.
Key details
NBOMe compounds are potent synthetic psychedelics. They are not part of the standard 5-, 10- or 12-panel or DOT tests.
Detection requires a dedicated mass-spectrometry assay; routine workplace panels will not identify them.
Their detection window is short and the compounds are potent, which is why specialised testing is uncommon outside clinical settings.
How NBOMe (25I-NBOMe) is tested
Not on standard panels; requires a dedicated LC-MS/MS assay. Urine detection is typically short, often under 24 hours. Screening immunoassays are presumptive — a non-negative screen is confirmed by GC-MS or LC-MS/MS at a lower cutoff before it is reported as positive. It is not part of the standard 5-, 10- or 12-panel or DOT tests.
Legal status
Schedule I.
Frequently asked questions
How long does nbome (25i-nbome) stay in your system?
In urine, typical detection is roughly 6–24 hours (specialised assay). Hair can detect use for up to 90 days and saliva/blood windows are usually shorter.
Will nbome (25i-nbome) show up on a standard drug test?
No — NBOMe (25I-NBOMe) is not part of the standard 5-, 10- or 12-panel or DOT tests. It would require a specialised or expanded assay.
How accurate are these detection windows?
They are typical ranges from published literature and assay documentation, not guarantees. Clearance depends on dose, frequency, metabolism and the specific test cutoff used.
NBOMe (25I-NBOMe) testing by state
Related substances
Cite this page
DrugPanels. “NBOMe (25I-NBOMe) Detection Time.” https://drugpanels.com/detection/25i-nbome/. Accessed 2026-09-11.
Sources
- NIDA research monographs on drug testing and pharmacokinetics — National Institute on Drug Abuse — nida.nih.gov
Detection windows describe typical ranges from the published literature and assay documentation; individual results vary. See our methodology.