Clonidine Detection Time

Central alpha-2 agonist · Rx, unscheduled.

Quick answer

Clonidine is typically detectable in urine for not tested / no interference after any use. It is not part of standard employment panels.

Not screened on standard employment panels.

Typical cutoff: Never screened.

Detection window by test type

urine
Any usenot tested / no interference
saliva
Any usen/a
hair
Any usen/a
blood
Any usen/a

Ranges reflect typical published detection windows and vary with dose, frequency, body composition, hydration and the assay used.

Key details

Clonidine (used for blood pressure, ADHD adjunct and opioid withdrawal symptoms) never appears on drug panels and produces no false positives in assay validations. Continue prescribed use normally.

Frequently asked questions

How long does clonidine stay in your system?

In urine, typical detection is not tested / no interference (any use). Hair can detect use for up to 90 days and saliva/blood windows are usually shorter.

Will clonidine show up on a standard drug test?

No — Clonidine is not part of the standard 5-, 10- or 12-panel or DOT tests. It would require a specialised or expanded assay.

How accurate are these detection windows?

They are typical ranges from published literature and assay documentation, not guarantees. Clearance depends on dose, frequency, metabolism and the specific test cutoff used.

Need an actual test?
Order online and visit a certified collection site — no doctor's order needed.
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Cite this page

DrugPanels. “Clonidine Detection Time.” https://drugpanels.com/detection/clonidine/. Accessed 2026-09-10.

Sources

  • Immunoassay cross-reactivity and validation documentation (FDA 510(k) summaries) — U.S. Food and Drug Administrationaccessdata.fda.gov

Detection windows describe typical ranges from the published literature and assay documentation; individual results vary. See our methodology.

Reviewed for sourcing accuracy against SAMHSA, FDA and peer-reviewed references. Last updated 2026-09-10. Educational information only — not medical or legal advice.