Quick answer
Oxycodone (Percocet, OxyContin) is typically detectable in urine for 1–3 days after occasional use; 3–4 days after regular use. It is screened on standard 10-panel, 12-panel drug tests.
Screened on: 10-panel 12-panel
Typical cutoff: Expanded urine: 100 ng/mL initial/confirm (oxycodone or noroxycodone).
Detection window by test type
| urine | |
|---|---|
| Occasional use | 1–3 days |
| Regular use | 3–4 days |
| saliva | |
| Any use | 1–2 days |
| hair | |
| Any use | up to 90 days |
| blood | |
| Any use | ~24 hours |
Ranges reflect typical published detection windows and vary with dose, frequency, body composition, hydration and the assay used.
Key details
Percocet contains oxycodone plus acetaminophen; the acetaminophen is irrelevant to testing. Oxycodone needs its own assay slot — legacy 5-panel opiate tests (morphine/codeine-focused at 2,000 ng/mL) often miss it, which is why 10/12-panel cups add an OXY strip.
A valid prescription verifies as negative through the MRO; keep the bottle or pharmacy record handy during hiring screenings.
Extended-release formulations (OxyContin) linger marginally longer than instant-release Percocet.
False positives & cross-reactivity
- No significant oxycodone false positives documented on modern assays; poppy seeds affect morphine/codeine results, not oxycodone strips.
Frequently asked questions
How long does oxycodone (percocet, oxycontin) stay in your system?
In urine, typical detection is 1–3 days (occasional use); 3–4 days (regular use). Hair can detect use for up to 90 days and saliva/blood windows are usually shorter.
Will oxycodone (percocet, oxycontin) show up on a standard drug test?
Yes — Oxycodone (Percocet, OxyContin) is screened on standard panels (10-panel, 12-panel).
Can anything cause a false positive for oxycodone (percocet, oxycontin)?
No significant oxycodone false positives documented on modern assays; poppy seeds affect morphine/codeine results, not oxycodone strips.
How accurate are these detection windows?
They are typical ranges from published literature and assay documentation, not guarantees. Clearance depends on dose, frequency, metabolism and the specific test cutoff used.
Related substances
Cite this page
DrugPanels. “Oxycodone (Percocet, OxyContin) Detection Time.” https://drugpanels.com/detection/oxycodone/. Accessed 2026-09-10.
Sources
- FDA drug labeling and pharmacokinetic data (DailyMed) — U.S. Food and Drug Administration — dailymed.nlm.nih.gov
- SAMHSA drug testing resources and analyte specifications — Substance Abuse and Mental Health Services Administration — samhsa.gov
Detection windows describe typical ranges from the published literature and assay documentation; individual results vary. See our methodology.