5-Panel Drug Test

The federal standard since the Reagan era — still the DOT-mandated panel for CDL drivers, aviation, maritime and other safety-sensitive work. Benzos, MDMA, methadone, oxycodone, suboxone, fentanyl, barbiturates, kratom, shrooms, LSD.

Quick answer

The 5-Panel Drug Test screens for 5 analytes: THC (marijuana), Cocaine (benzoylecgonine), Opiates (morphine, codeine, 6-MAM heroin marker), Amphetamines (Adderall class), PCP.

Analytes and cutoffs

AnalyteScreen cutoff
THC (marijuana)50 ng/mL urine initial / 15 confirm
Cocaine (benzoylecgonine)150 / 100 ng/mL
Opiates (morphine, codeine, 6-MAM heroin marker)2,000 / 2,000 ng/mL
Amphetamines (Adderall class)500 / 250 ng/mL
PCP25 / 25 ng/mL

Cutoffs are typical urine immunoassay screen thresholds; confirmation cutoffs are lower. Values vary slightly by manufacturer.

Frequently asked questions

What does the 5-Panel Drug Test test for?

It screens for 5 analytes: THC (marijuana), Cocaine (benzoylecgonine), Opiates (morphine, codeine, 6-MAM heroin marker), Amphetamines (Adderall class), PCP.

How accurate is the 5-Panel Drug Test?

Screening immunoassays are presumptive; any non-negative result is confirmed by GC-MS or LC-MS/MS at a lower cutoff before it is reported as positive.

What does the 5-Panel Drug Test miss?

The federal standard since the Reagan era — still the DOT-mandated panel for CDL drivers, aviation, maritime and other safety-sensitive work. Benzos, MDMA, methadone, oxycodone, suboxone, fentanyl, barbiturates, kratom, shrooms, LSD.

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